Uncharted: Drake’s Fortune zal je ongetwijfeld laten denken aan de avonturenreeks van Tomb Raider. De game is dan ook deels ‘n beetje vergelijkbaar met Tomb Raider, maar verschilt ook op diverse vlakken. Evan Wells, co-president bij Naughty Dog begrijpt de vergelijking maar geeft aan dat de insteek van de gameplay en de personages wezenlijk verschillen ten opzichte van die van Tomb Raider. “Het gaat bij beide om schattenzoekers, maar verder zijn er de nodige verschillen tussen beide”.
“I think just by the very fact that both Nathan Drake and Lara Croft are treasure hunters, there will be comparisons. But beyond that, they diverge pretty rapidly. From a character standpoint, Nathan Drake is an everyman who struggles to get by, who you can see on his face that he’s stressed out as he’s flinching from bullets ricocheting off the cover he’s hiding behind, while Lara is the more stone-faced acrobat, perfect landing every time,” he said. “And then the gameplay, obviously we were very focused on third-person cover-based play, while theirs is more auto-aiming and a little more heavy on the puzzle-solving.”